The Birth Control Pill & The Breast Cancer Connection

There is only one drug in the world so well known that it's called "the Pill." For more than forty years, more people have taken "the Pill" than any other prescribed medicine in the world.


Sex, pregnancy, and contraception have been hot topics for millennia. It wasn't until the U.S. government approved the birth control pill in 1960 that possibilities for contraception changed dramatically. The majority of women -- and plenty of men -- welcomed "the Pill".

The birth control pill was the first medication ever designed for purely social, rather than therapeutic purposes. At the height of the drugs popularity, U.S. Senate hearings focused the nations attention on potentially deadly health risks posed by the high-dose Pill. As a result of the hearings, pharmaceutical companies lowered the dosages and doctors advised women who were obese, smoked, had high blood pressure or a family history of blood clots against taking the Pill.

In the 1980s, the high dosage 10-milligram pill was removed from the market and biphasic and triphasic oral contraceptives were introduced. Today, women can get a prescription for a Pill containing 1 milligram of progestins, one tenth of the original dose, and containing as little as 20 micrograms of estrogen.

From the very beginning, a significant number of women complained of discomfort from the Pill and switched to other methods. When women wanted to discuss the side effects with their doctors, they often met with frustration. It was common for their complaints to be dismissed as exaggerated. In other cases their ailments were just considered the price that women had to pay in return for such an effective contraceptive. The problem was compounded by that fact that female patients were not always informed about the potential for strokes, heart attacks or blood clots while on the Pill. For the most part sharing "the Pills" risk has become a part of the information provided by health care practitioners who prescribe the Pill.

Today, the safety of the Pill is assumed. However, it is important to remember that the pill contains identical hormones to those found in Hormone Replacement Therapy (HRT). HRT has come under question because of the Women's Health Initiative Study showing an increase in breast cancer and heart disease for those women who were on HRT.

In October 20, 2004 headlines read "Birth Control Pill Cuts Cancer, Heart Disease Risk: Study - A new study, yet to be published, suggests women who use oral contraceptives have lower risks of heart disease, stroke, and cancer."

This study has now been denied as accurate by the WHI. Analyses by the WHI have made it clear that the recent findings were not correct?

The low dose pill today although deemed to be safe has never undergone a large government-funded study similar to the WHI study on HRT. According to Dr. John R. Lee in his book "What Your Doctor May Not Tell You About Breast Cancer" women up to age 21 who use the Pill increase their lifetime risk of Breast Cancer by 600%. Caution when considering the use of Birth Control Pill should still be used.

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Solution To Breast Cancer!

How long should a patient take tamoxifen for the treatment of breast cancer?

Patients with advanced breast cancer may take tamoxifen for varying lengths of time, depending on their response to this treatment and other factors. When used as adjuvant therapy for early stage breast cancer, tamoxifen is generally prescribed for 5 years. However, the ideal length of treatment with tamoxifen is not known.


How Often Should I Take Tamoxifen?

Two studies have confirmed the benefit of taking adjuvant tamoxifen daily for 5 years. These studies compared 5 years of treatment with tamoxifen with 10 years of treatment. When taken for 5 years, the drug reduces the risk of recurrence of the original breast cancer and also reduces the risk of developing a second primary cancer in the other breast. Taking tamoxifen for longer than 5 years is not more effective than 5 years of therapy.

What is Tamoxifen

Tamoxifen is an oral selective estrogen receptor modulator which is used in breast cancer treatment, and is currently the world's largest selling breast cancer treatment. It is used for the treatment of early and advanced breast cancer in pre- and post-menopausal women. It is also approved by the FDA for the reduction of the incidence of breast cancer in women at high risk of developing the disease. It has been further approved for the reduction of contralateral (in the opposite breast) breast cancer.

Tamoxifen and Cancer

Tamoxifen is used to reduce the risk of breast cancer for women who:

1. are at high risk of breast cancer but have no personal history of the disease
2. have non-invasive, hormone-receptor-positive breast cancer, or DCIS (ductal carcinoma in situ)
3. have hormone-receptor-positive invasive breast cancer at any stage.

Tamoxifen is sometimes used to treat gynecomastia in men. Tamoxifen is also used by bodybuilders in a steroid cycle to try and prevent or reduce drug-induced gynecomastia caused by steroids that are used in the same cycle.

Tamoxifen is also used to treat infertility in women with anovulatory disorders. A dose of 10-40 mg per day is administered in days 3-7 of a woman's cycle.

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Increasing Accuracy and Patient Comfort With Digital Mammography

There's encouraging news for women. Not only is it becoming easier to catch and treat breast cancer in its earliest stages, but new technologies are making the process of diagnosing the disease more comfortable for the patient-and more accurate as well.


The National Cancer Institute recommends mammography screenings every one to two years for women over 40 and annually for women over 50. In addition, women at high risk of developing breast cancer (for example, women with a strong family history of breast cancer or who test positive for the BRCA breast cancer gene) are encouraged to begin annual mammography screenings even earlier-sometimes as young as 25-and should consult a physician.

Benefits and risks

• Early detection of small breast cancers greatly improves a woman's chances for successful treatment. If breast cancer is caught and treated while it is still confined to the breast ducts, the cure rate is close to 100 percent.

• Clinical studies in the U.S., Sweden and the Netherlands have suggested that deaths from breast cancer could be cut by between 36 and 44 percent if screening mammography were performed annually on all women in their 40s.

Digital mammography

One of the most recent advances in breast cancer screening is digital mammography. Digital mammography uses essentially the same system as conventional mammography, but is equipped with a digital receptor and a computer instead of a film cassette.

Digital mammography systems such as Siemens Medical Solutions' Mammomat® NovationDR enable faster and more accurate viewing of the dense tissue of the breast. Images are acquired digitally and displayed immediately on the system monitor.

According to a recent study published in the New England Journal of Medicine, digital mammography was significantly better than conventional mammography at screening women in any of the following categories:


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Delivering A Basket Of Hope For Women

Some unique hardwood maple baskets woven by artisans in Ohio have been used to deliver hope-bringing millions of women potentially life-saving information about breast cancer.


Through sales of these baskets, Horizon of Hope®, a partnership among The Longaberger Company, nearly 60,000 independent Longaberger home consultants and the American Cancer Society (ACS), has raised nearly $12 million for ACS since 1995 and reached an estimated 18 million women.

In 2005, more than 200,000 Horizon of Hope baskets and thousands more related products were purchased. Every year, $2 from the sale of each basket and other campaign products go to ACS to fund research and education programs.

"We truly are at our best when we gather together, and Horizon of Hope allows us to unite our sisterhood behind a cause that touches nearly all women in some way," said Tami Longaberger, chief executive officer of The Longaberger Company. "Thanks to the amazing efforts of our 60,000 home consultants, millions of women are benefiting from life saving breast cancer research and education."

Many home consultants plan their own Horizon of Hope annual community events.

Susan Kantor of Bartlett, Ill., is preparing for her tenth Horizon of Hope event, and nearly 1,000 guests are expected to attend. Kantor says attendance has continually grown every year since her team's first event, and this year cumulative donations will exceed the $300,000 mark. A committee of 20 women on her sales team plans all details of the event for months before it takes place, and many more team members are involved by inviting friends and helping out at the event.

"Horizon of Hope gives me, my sales team, our customers and other friends a chance to do something wonderful for all women," says Kantor. "This is a cause that unites us because it has touched so many of us in some way."

Theresa Razzante from Highland Heights, Ohio, also plans annual events with her team that she says have had immediate and positive results. This year is her team's eleventh event, with more than 500 expected to attend.

"For months after our dinner one year, I had ladies share stories with me that they went for a mammogram-some their first one ever-because of our event," said Razzante. "I feel like I am making a difference in my community and in my families' and friends' lives."

The Horizon of Hope Web site, www.horizonofhope.com, includes testimonials, information on funded programs and studies, and important prevention steps.

The 2006 basket was designed as a jewelry box and features wood splints bent into the signature pink ribbon design, symbolic of breast cancer support.

Offered in either Warm Brown or Whitewashed, the baskets are priced at $36 each or two for $64; a solid-wood lid in either color with a wood knob is available for $18, and a drawstring fabric liner is available for $14.

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Breast Cancer Treatment: Conventional Treatment Methods

Your team of doctors will make treatment recommendations based on the stage of your cancer. Your standard treatment options may include surgery, chemotherapy, radiation, and hormone therapy. If you have been diagnosed with DCIS or LCIS, your stage is the lowest and the road you will travel will be easier. For DCIS, your options may include breast-conserving surgery or mastectomy with or without radiation and hormone therapy.


LCIS treatments options are a bit different. They include observation to determine changes, hormone therapy to prevent cancer from developing, or bilateral prophylactic (preventive) mastectomies.

Things get more complicated when your cancer spreads beyond the ducts or lobes/lobules. Once your cancer has been staged, you can visit www.cancer.gov to determine your treatment options. They will typically include: surgery, chemotherapy, radiation, and/or hormone therapy. For IBC, treatment options are similar to the other types of breast cancer, but they will always include chemotherapy because of its aggressiveness.

•    Surgery: Breast surgery can be either a lumpectomy, where the tumor is removed, or a partial or modified radical mastectomy. With a lumpectomy, it is typically followed by radiation. This way, you get to keep your breast and studies have shown no difference in survival rates between lumpectomy/radiation and mastectomy. 

Note: Not too long ago, they used to perform radical mastectomies where the breast, all the lymph nodes, and the underlying muscle were cut away. Thankfully, medicine has discovered that's not necessary. Now, a partial or modified radical mastectomy is performed, where either part of the breast tissue, or the entire breast, and possibly a portion of the lymph nodes, are removed. On the whole, a mastectomy isn't too bad a surgery, although everyone is different. I found both of mine to be quite easy, but you will wake up with drain tubes, which you’ll typically have for at least a week.

•    Chemotherapy: Chemotherapy is defined by Wikipedia as “the use of chemical substances to treat disease. In its modern-day use, it refers primarily to cytotoxic drugs used to treat cancer.” This can be a frightening prospect for anyone. We've all heard horror stories about how very debilitating chemotherapy can be. However, much progress has been made in the management of chemo's side effects, to the point that, once you have the right management tools, you can continue to enjoy the activities you typically do. Chemo is a means of treating your cancer systemically and is typically recommended for those whose tumor is larger than a certain size and/or the cancer has spread to your lymph nodes. The thinking is that if your cancer has had the opportunity to access the rest of your body, your treatment should be systemic as well.

•    Radiation: Radiation therapy is typically a localized treatment option, where rapidly dividing cells are damaged. Cancer cells are very rapid dividers, so radiation is an effective option. Typically, radiation therapy is given for about six weeks, five days a week. It's very much like lying still for an x-ray, only instead of lasting a second or two, it lasts a couple of minutes. It can cause fatigue, toward the end and slightly after, and can cause a sunburn effect on your skin.


•    Hormone Therapy: Many breast cancers are hormone-dependent. In these cancers, there are receptors on the tumor that can be filled with estrogen. The thinking is that when estrogen fills these receptors, it causes the tumor to grow. This is called estrogen-receptor positive (ER). These cancers respond well to hormone therapy and the hormone therapy drug that will be recommended for you will depend on your menopausal status. These drugs are in pill form and you take them once a day. The most popular of these drugs, for pre-menopausal women, is Tamoxifen and, for post-menopausal women Femara or Arimidex.  There is new evidence that suggests that taking Femara, after taking Tamoxifen for five years, increases survival rates.

•    Immunotherapy: There is a fourth modality of treatment on the horizon and it's called Immunotherapy. This involves getting your immune system to fight your cancer and there is, and will be, a lot of research being done in this area.

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Breast Cancer Treatment: Surviving Chemotherapy

Chemotherapy is a word that strikes fear into most of our hearts.  We've seen the movies and heard such horrible stories about undergoing this difficult treatment for a disease that could very well kill us.  I underwent chemo for breast cancer and know that, in some cases, the cancer isn't hard … it isn't painful … it doesn't make us sick.  That's the case for most of us who have breast cancer, but don't have distant metastases.  But then, they say we need to do chemo and we know we'll feel that.


Although chemo drugs haven't changed that much, and they're still terribly hard on our bodies, the management drugs have changed a lot.  Chemotherapy, for many of us, isn't the show-stopper we thought it would be.  Of course, each of us is different and the chemo drugs affect each of us in different ways, but, for the most part, chemo is definitely doable.  

My breast cancer was Stage IIIa, with a 5.8 cm tumor, 8 of 10 lymph nodes positive, and I was only 39 years old.  That bought me a ticket for the chemo ride.  And I was scared out of my wits.  But, I found an online breast cancer support group, at WebMD, and those women told me everything to expect and more.  I went through four rounds of adriamycin and cytoxan.  Both of them are some pretty stout breast cancer chemo drugs.  After that, I did a controversial treatment that involved extremely high doses of cytoxan, taxol, and cisplatin, so I learned quite a bit about surviving chemotherapy.

First of all, I would highly recommend getting a port.  This is a line that goes into a vein in your chest, the entrance to which sits just under your skin, right below your collarbone.  It requires a quick surgery to put it in but, if you're having a mastectomy for your breast cancer, you can get the chemo port put in at the same time.  If you choose not to do that, you'll have to get your chemo treatments through your veins and chemo is really hard on your veins.  This means that you will, most likely, have to endure multiple attempts for them to find a vein, as time goes by.  With the port, it's already in a vein, so all they have to do is stick the needle into the port to access it.  If you find this uncomfortable, there is a cream they can give you called Emla cream.  One of the first things I learned was to tell them the moment I was uncomfortable.  It's all fixable.  You'll put the Emla cream on a bit before you have to have your port accessed and it'll numb your skin.

Most breast cancer chemotherapy drugs will cause your hair to fall out.  This is because chemo kills the rapidly dividing cells in your body.  Your mucous areas and hair follicles are affected for this reason.  That's why you may have nausea or develop mouth or throat sores.  Again, all this sounds scary, but is totally manageable.  Since you will probably be losing your hair, which can be quite traumatic, I would advise going wig or hat shopping before you even get your first chemo.  Take a girlfriend with you and be adventurous.  Try on different styles, and even colors.  If you've always wanted to be a blonde, now's your chance!  Make a day of it and have fun with it.  Goodness knows, you have to look for that silver lining every chance you get.  Also, make sure to have your nausea med prescription filled before you go so you'll have it waiting for you if you need it at home.  You may be pretty tired, afterward, so don't wait till then to get those meds.

On your first chemo day, they will probably give you some steroids, intravenously or through your port, to help with the nausea.  This may make you hungry; it sure did for me!  But, I would recommend you don't eat your favorite food on chemo day.  Chemo is manageable, but after you're all done, you may find that you have associations.  For example, I used to love the cucumber melon fragrance when I was going through chemo.  I had cucumber melon everything!  But, to this day, the smell of cucumber melon makes my stomach do a little somersault because it reminds me of such an unpleasant time in my life.  The same can happen with food.  I still can't look a chicken burrito in the eye!  But, I'm sure glad I didn't eat a taco because I would've hated for that to be ruined for me!

Many breast cancer chemo drugs are hard on your bladder, so be sure to drink, drink, drink.  If you don't feel like drinking water, then broth, jello, or even popsicles will help.  Since you've gotten your nausea meds all filled in advance, be sure to take them as prescribed, whether you think you need them or not.  Chemo nausea isn't just any kind of nausea and it's much easier to stay ahead of it than to try to fix it once it occurs.  If you do happen to get nauseated, and I can't stress this enough, call your doctor!!!  There are many, many nausea meds and you do not have to feel sick just because you're doing chemo.  Once they find the right drug for you, it will be so much easier.  So, do not suffer this in silence!  The same applies for if you get sores in your mouth or throat.

You will be tired from this treatment.  Most of us get more tired as the treatments progress because they make our white blood cell counts drop really low.  Because of this, it's a good idea to keep some Purell, or something similar, with you all the time for use when you've had to touch, for example, public restroom door handles.  Your risk of infection will be much higher during this time.

If you lose your hair, it will typically happen in 10-14 days after your first chemo treatment.  If you have long hair, you might want to cut it short in preparation.  I know I felt so out of control of everything, during that time.  When your hair comes out, it lets go quickly and in large clumps, getting all over your pillow and clogging your drain.  For many women, that is more traumatic than even losing a breast.  So, I figured that was the one thing I could control about this whole breast cancer thing … when my hair came out.  I cut it really short, beforehand and, when it started to let go, I had my husband get the clippers and shave my head.  My daughter helped and we did a little Mohawk and stripe action first!

That was my way of shaking my fist at this cancer … it might take my breasts, and it might take my hair for a while, but I beat it to the punch!  It was my way of saying, "You cannot take my spirit!"  You can do the same thing.  Your breast cancer does not define you.  It is but a speed bump in the course of your life.  Strap on your gloves and step into the ring.  This chemo is your biggest punch.  Your spirit is your own and that breast cancer can't touch it!

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Breast Cancer Risk

If young women take certain simple steps when they are adolescents, they may reduce risk of breast cancer later in life. A research suggests that puberty could be a crucial time for development of breast cancer.


Regular exercise is believed to delay the beginning of a girl's first menstrual period. That is when the body creates hormones that stimulate the majority of breast cancers. According to a study, just 4 hours of weekly exercise can postpone hormone surges for up to 12 months.

Four hours a week is not a large amount of activity for a girl. She can play dodge ball, play on the playground or ride her bike. Because exercise can lower hormone activity, it can reduce risk of breast cancer, even after a girl starts having periods.

One more way is cutting back on fat. Girl who cut her fat intake by only 6 percent lowered her estrogen and progesterone levels by at least 30 percent, according to a study. These theories are not really well tested and need more research.

Breast cancer is the most common cancer in women, other than skin cancer. In the United States approximately 183,000 new cases are diagnosed and about 41,000 women die each year from cancer originating in the breast.


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